Collagen is used as a bone graft substitute and added in bioceramics and other osteoconductive materials that are used in the regeneration and repair of bone. The addition of collagen in these materials encourages cell growth that is needed for tissue regeneration and improves the handling properties of the bone void filler including the spine.

Collagen scaffolds can be designed to mimic and regenerate native tissues and are being increasingly used in cartilage repair.
Resorbable membranes and wraps protect underlying tissues in the case of tendon trauma. Collagen tendon wraps are excellent materials for the repair of soft tissue, achilles tendon, patellar tendon, biceps, quadriceps and more.