A summary of 12 studies (n=753) on oral fish collagen supplementation, found statistically significant improvements in skin hydration, elasticity and wrinkle depth versus placebo, with no adverse events reported across the pooled studies.
Sodium hyaluronate is included at the exact dose (120 mg/day) used in a 12-week randomized trial that showed measurable improvement in wrinkle score, hydration, and trans epidermal water loss.
Vitamin C is included at a modest margin above the RDA
to support the hydroxylation step collagen synthesis depends on.
eSciPub meta-analysis, 2023
MDPI Nutrients, 2021 — oral hyaluronan RCT
NIH ODS — Vitamin C
Hydrolyzed marine collagen peptide (Type I, <5 kDa)
Stick pack sachet,
RTD beverage or
capsule/tablet
